{"product_id":"varinil-10mg-tablets","title":"Varinil 10mg Tablets","description":"\u003cp\u003eVarinil 10mg contains Amlodipine which is a dihydropyridine calcium–channel blocker. It is a peripheral and coronary vasodilator, but, unlike the calcium–channel blockers verapamil or diltiazem, has little or no effect on cardiac conduction and negative inotropic activity is rarely seen at therapeutic doses. Administration of Amlodipine results primarily in vasodilatation, with reduced peripheral resistance, blood pressure, and afterload, increased coronary blood flow, and a reflex increase in heart rate. This in turn results in an increase in myocardial oxygen supply and cardiac output.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow to use\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eHypertension and stable angina pectoris: The usual dose is 5mg once daily. If necessary, this may be increased to 10mg once daily.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrecautions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eAmlodipine should be used with caution in patients with hypotension, in patients whose cardiac reserve is poor, and in those with heart failure since deterioration of heart failure has been noted. Amlodipine should not be used in cardiogenic shock, in patients who have recently suffered a myocardial infarction, or in acute unstable angina. amlodipine should not be used to treat an anginal attack in chronic stable angina. In patients with severe aortic stenosis Amlodipine may increase the risk of developing heart failure. Sudden withdrawal of Amlodipine might be associated with an exacerbation of angina. The dose may need to be reduced in patients with hepatic impairment. Amlodipine should be discontinued in patients who experience ischaemic pain following its administration\u003c\/span\u003e\u003c\/p\u003e","brand":"Optum Health Pharmacy","offers":[{"title":"112's","offer_id":52521006399788,"sku":null,"price":1400.0,"currency_code":"KES","in_stock":false},{"title":"28's","offer_id":52521006432556,"sku":null,"price":405.0,"currency_code":"KES","in_stock":true},{"title":"14's","offer_id":52521006465324,"sku":null,"price":200.0,"currency_code":"KES","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0844\/6895\/7484\/files\/prescription-required.png?v=1745497922","url":"https:\/\/optumhealthpharmacy.africa\/products\/varinil-10mg-tablets","provider":"Optum Health Pharmacy","version":"1.0","type":"link"}